Childhood Disintegrative Disorder (CDD): Unravelling the Mystery of Late Onset Autism

Lungamhlongo
4 min readJul 21, 2023

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Delving into the Relationship between Autism and Childhood Disintegrative Disorder

Introduction

We have so far covered five developmental conditions or disorders that are confused with autism, and they are Savant Syndrome, Rett’s Syndrome, Tourette’s Syndrome, Social Communication disorder (SCD), and Asperger’s Syndrome. Today, we are on the sixth condition, and it’s called Childhood Disintegrative Disorder (CDD).

In this blog post, we will explore the history, causes, prevalence, and gender differences of CDD. Additionally, we will learn the relationship between CDD and autism, its classification as Disintegrative Psychosis Late Onset Autism, and the phenomenon of regression autism.

My aim (in case you’re wondering), is to provide an informative and unbiased understanding of CDD while highlighting its differences from autism. Now that I’ve cleared the air, let us begin.

Childhood Disintegrative Disorder (CDD) is a rare and enigmatic condition that has often been confused with autism due to overlapping characteristics. CDD falls under the umbrella of Autism Spectrum Disorders (ASD), but it stands apart due to its distinct pattern of late onset and dramatic regression. Let me give you a quick rundown on the history of this condition.

History and Characteristics of Childhood Disintegrative Disorder (CDD)

Childhood Disintegrative Disorder, also known as Heller’s Syndrome, was first described by Austrian educator Theodor Heller in 1908. CDD is a very rare neurodevelopmental disorder that typically manifests in children aged 3 to 4 years.

Initially, children with CDD appear to have a normal developmental trajectory, showing age-appropriate social, communication, and motor skills.

However, between the ages of 2 and 10, they undergo a significant regression in multiple areas, losing previously acquired language, motor skills, social interaction abilities, and toileting skills.

Causes and Prevalence of Childhood Disintegrative Disorder

The exact causes of CDD remain unclear, and ongoing research is focused on unravelling its origins. Some theories suggest a possible genetic component, while others explore the role of neurological factors.

This mental disorder is incredibly rare, accounting for less than 1% of autism cases. It is more common in boys than girls, with a male-to-female ratio of approximately 4:1, though the reasons for this gender disparity are not yet fully understood.

Similarities and Differences between CDD and Autism

Autism and Childhood Disintegrative Disorder share some commonalities, primarily in terms of impaired social communication and restricted, repetitive behaviours. However, the key distinction lies in the age of onset and the pattern of regression.

Autism typically presents before the age of 3 and displays a more continuous and stable developmental trajectory. In contrast, CDD’s late onset and abrupt regression set it apart, leading to a significant loss of skills over a short period.

Signs, Symptoms, Diagnosis, and Treatment of Childhood Disintegrative Disorder

The signs and symptoms of CDD vary depending on the child, but common indicators include loss of language, social withdrawal, repetitive behaviours, and motor skill regression. Diagnosing CDD can be complex, often requiring input from multiple specialists, including paediatricians, neurologists, and psychologists.

Early intervention and individualized therapy programs are vital to improving the quality of life for children with CDD. Behavioural therapies, speech therapy, occupational therapy, and educational support can be effective in managing the condition and helping children develop new skills.

The Confusion with Autism

The confusion between CDD and autism stems from their shared features, such as language and social communication deficits. However, their differing developmental courses and regression patterns underscore their distinction.

While both fall under ASD, the late onset and regression seen in CDD led to its classification as Disintegrative Psychosis Late Onset Autism. This label recognizes its relation to autism but acknowledges the uniqueness of CDD’s presentation.

Conclusion

Childhood Disintegrative Disorder remains a mysterious condition, often overshadowed by its more prevalent counterparts within the autism spectrum.

By understanding its distinct characteristics and recognizing the differences between CDD and autism, we can foster greater awareness and compassion for individuals and families impacted by this rare disorder. Early diagnosis and comprehensive intervention are crucial in offering the best possible support and resources to help children with CDD thrive.

Do you have questions about Childhood Disintegrative Disorder (CDD)? (FAQs)

Is CDD a form of autism?

CDD falls under the umbrella of Autism Spectrum Disorders, but it is a separate and distinct condition due to its late onset and regression pattern.

What are the early signs of CDD?

Early signs of CDD may include delayed language development, difficulty with social interactions, and repetitive behaviours.

Are there any known genetic factors contributing to CDD?

While research suggests possible genetic links, the exact genetic factors contributing to CDD remain unclear.

What is the prevalence of CDD in the general population?

CDD is incredibly rare, accounting for less than 1% of autism cases.

Can children with CDD improve with treatment?

Early intervention and individualized therapy programs can significantly improve the quality of life for children with CDD by helping them develop new skills and adapt to their challenges.

For further information on signs, symptoms, diagnosis, and treatment, you can visit the Centre for Disease Control and Prevention (CDC). They are a leading public health agency. They provide reliable and up-to-date information on various topics, including neurodevelopmental disorders like autism and CDD.

Or Mayo Clinic, this renowned medical institution known for its expertise in various medical specialties. They are a good source of reliable and comprehensive information about medical conditions, including autism and other developmental disorders.

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